Tuesday, April 14, 2009

What Causes Lung Cancer?


By Randolph Meresmaa

Lung cancer is responsible for 1.3 million deaths worldwide. It is the most common cause of cancer related deaths among men and second most common among women. Unfortunately the deaths are increasing not decreasing.

1. Smoking

No surprise here, smoking is the leading cause. Almost 90% of this disease is caused by smoking in the developed world. The risk of developing it for male smokers is 17.2% and 11.6% for female smokers. So the risk factor is very high. If you are a nonsmoker then the risk of having lung cancer is 1.3% for men and 1.4% in women. The changes of developing it is influenced by the time a person smokes and also by the rate a person smokes. And if a person stops smoking then the risk of cancer will steadily decrease because damage to the lungs is repaired slowly. Passive smoking is also a cause of cancer among nonsmokers. Someone living or working with smoker(s) is considered a passive smoker. If you live with a smoker, you have 2 to 3 times the risk of developing this disease compared with a person who lives in a nonsmoking environment.

2. Radon Gas

Radon exposure is the second major cause, after smoking. Radon is a gas that is generated by the breakdown of radioactive radium, it is colorless and odorless. This process of breaking down radium can cause mutations that sometimes can turn cancerous. The levels of radon gas vary by the composition of underlying soil and rocks. The United States Environmental Protection Agency (EPA) estimates that one in 15 homes in the United States has radon levels that are above the recommended guideline.

3. Asbestos

Asbestos is a material that is used in construction. In the UK, asbestos accounts for 2-3% of male lung cancer deaths. Asbestos can enter the body by being inhaled or swallowed. Contact with asbestos over time has been linked with the disease. Most contact with asbestos is work-related. There is also a synergistic effect between smoking tobacco and asbestos in the formation of lthe disease.

4. Viruses

Viruses are known to cause this disease among animals and recent evidence has shown the there is a similar potential in humans as well. Implicated viruses include human papillomavirus, JC virus, simian virus 40, BK virus, and cytomegalovirus. These viruses may affect the cell cycle and inhibit apoptosis, allowing uncontrolled cell division.

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